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A man whose brain injury left him unable to walk or talk for eight years regained full consciousness 20 minutes after taking the sleeping pill Ambien.
The 39-year-old from Amsterdam - referred to only as Richard in the medical journal Cortex - was diagnosed with akinetic mutism at age 29. He suffered the rare mental disorder after choking on a piece of meat, which starved his brain of oxygen and robbed him of his ability to perform basic tasks.
Richard was only able to respond to questions or commands by making gestures with his eyes, but did not move voluntarily and had to be fed through a tube.
Doctors said they decided to give him zolpidem - sold in the UK as Stilnoct, and in the US as Ambien - as a last resort, following reports of the sleeping pill temporarily curing patients of paralysis in studies around the world.
Within 20 minutes Richard was able to walk with the help of his carers and phone his father, who had not heard his son's voice in nearly a decade.
Writing in the journal, medics said giving Richard the drug once a day could keep him alert for two hours. But the medication would start to lose its impact if taken for five days on the trot because his body would become tolerant of it.
Akinetic mutism does not physically paralyse people, but it slows their mental function down so much that the brain struggles to send signals to the body to move, talk or eat. Researchers believe Ambien helps reopen these pathways.
A 39-year-old patients from the Netherlands - referred to only as Richard (right) in medical journal Cortex - was diagnosed with akinetic mutism at age 29. He suffered the rare mental disorder after choking on a piece of meat, which starved his brain of oxygen
Ambien is one of the most commonly prescribed in the US, outselling painkillers such as Percocet and maximum strength ibuprofen
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