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WCVB-TV reported on Friday that a toxicology test found methadone, fluoxetine, norfluoxetine, diazepam, nordiazepam and alcohol in her system.
Fluoxetine is an antidepressant, and diazepam is used to treat anxiety and alcohol withdrawal symptoms.
Hill was found unresponsive at a home at the Kennedy compound on Cape Cod on Aug. 1. She was pronounced dead at Cape Cod Hospital.
Hill was scheduled to start her senior year at Boston College this fall.
She was the daughter of Robert and Ethel Kennedy's fifth child, Courtney, and Paul Michael Hill.
FILE - In this Sept. 20, 2016, file photo, Saoirse Kennedy Hill, right, granddaughter of Ethel Kennedy and her late husband Robert F. Kennedy, holds a relative's baby before a ceremony for naming the Robert Kennedy Navy Ship at the John F. Kennedy Presidential Library in Boston. Authorities have determined that Saoirse Kennedy Hill, the 22-year-old granddaughter of assassinated presidential candidate Robert F. Kennedy, died of a drug overdose. She was found unresponsive at a home at the Kennedy compound on Cape Cod on Aug. 1. (AP Photo/Elise Amendola, File)
Hill had written frankly and publicly about her struggles with mental health and a suicide attempt while in high school.
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